Thermo Fisher Scientific RORB Recombinant Rabbit Monoclonal Antibody (7J9T7)
RORB 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 사람, 생쥐, 랫트 시료에 반응하며 HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7J9T7 |
| Immunogen | Synthetic peptide within amino acids 1–100 of human RORβ (UniProt ID: Q92753) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911876 |
Product Specific Information
- Positive test controls: PC-12, C6, SH-SY5Y, Y79, Mouse eye
- Immunogen sequence:
MCENQLKTKA DATAQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQQ NNASYSCPRQ RNCLIDRTNR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ
Target Information
Retinoid-related orphan receptor beta (RORβ) is a nuclear receptor (NR1 family) involved in the development and function of the central nervous system, including sensory input integration and circadian timing.
Disruption in mice leads to juvenile ataxia, retinal degeneration, circadian rhythm abnormalities, and delayed male fertility onset.
RORβ binds monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, RORβ2, is expressed in the pineal gland and retina, sharing common DNA- and ligand-binding domains with RORβ but differing in the amino-terminal domain.
Expression of RORβ is documented in multiple regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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