
Thermo Fisher Scientific Narsoplimab Recombinant Human Monoclonal Antibody
인간 MASP-2를 표적으로 하는 재조합 인간 단일클론 항체로, 보체 렉틴 경로 연구에 적합합니다. ELISA 등 다양한 응용 가능하며, CHO 세포에서 발현된 IgG4 람다형 항체입니다. 단백질 A/G로 정제되었으며, 안정적인 액상 형태로 제공됩니다.
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Thermo Fisher Scientific Narsoplimab Recombinant Human Monoclonal Antibody
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG4, lambda |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human MASP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.59 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911321 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Narsoplimab is a human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the lectin pathway of the complement system. The lectin pathway is one of the principal pathways of complement and is activated primarily by tissue damage and microbial infection. Inhibition of MASP-2 does not interfere with the classical complement pathway, preserving acquired immune response functions. This antibody is designed to prevent complement-mediated inflammation and endothelial damage while maintaining innate immunity integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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