Thermo Fisher Scientific NDE1 Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal NDE1 항체. Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 세포 중심체 관련 단백질 NDE1 검출용 연구용 시약.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NDE1. Recombinant protein control fragment (Product #RP-92277). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644529 |
Product Specific Information
Immunogen sequence:
KDEARDLRQE LAVQQKQEKP RTPMPSSVEA ERTDTAVQAT GSVPSTPIAH RGPSSSLNTP GSFRRGLDDS TGGTPLTPAA RISALNIVGD LLRKVGALES KLAS
Highest antigen sequence identity to the following orthologs:
- Mouse – 89%
- Rat – 83%
Target Information
NDE1 is a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 plays an essential role in microtubule organization, mitosis, and neuronal migration. Mutations in the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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