Thermo Fisher Scientific BMP-8B Polyclonal Antibody
Thermo Fisher Scientific의 BMP-8B Polyclonal Antibody는 인간 BMP-8B 단백질을 인식하는 토끼 유래 IgG 항체입니다. ICC/IF에 최적화되어 있으며, 액상 형태로 제공됩니다. 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 183–216. Recombinant protein control fragment (Product #RP-110010) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091872 |
Product Specific Information
- Immunogen sequence: DLQTLRAGDE GWLVLDVTAA SDCWLLKRHK DLGL
- Antigen sequence identity: Mouse 85%; Rat 82%
Target Information
BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors, leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. BMP-8B stimulates thermogenesis in brown adipose tissue, and its expression may be downregulated in pancreatic cancer. BMP-8B may have arisen from a gene duplication event, with a duplicate gene also present on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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