Thermo Fisher Scientific Haptoglobin (HP) Monoclonal Antibody (HP/4815)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Peptide Array (Array)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Positive Control: Human liver
• Cellular Location: Secreted; selective granular cytoplasmic expression in liver with distinct positivity in plasma and extracellular matrix.

Target Information

Haptoglobin is an α2-globulin plasma protein synthesized in the liver. It functions as an acute phase protein and scavenger of hemoglobin from hemolyzed red cells. The haptoglobin monomer consists of two α and two β chains; the α chains may be hp1Fa, hp1Sa, or hp2a types while the β chain is constant. Three major phenotypes are recognized: HP1-1, HP2-1, and HP2-2, in which the hp1a chain may be either the F or S type.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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