Thermo Fisher Scientific Human PRKG1, GST Tag Recombinant Protein

Thermo Fisher Scientific Human PRKG1, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: -

Product Specifications

Product Specific Information

For maximum recovery, spin prior to use.
Aliquots of the 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials in original packaging until exhausted.
For larger sizes, prepare aliquots to reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
Never store kinase diluted.
If properly stored at -80°C, this product is guaranteed for 6 months from the date of purchase.

PRKG1 is a cGMP-dependent serine/threonine kinase that plays an important role in the relaxation of vascular smooth muscle and inhibition of platelet aggregation.

Protein Form: Full Length

Target Information

PRKG1 is a cGMP-dependent serine/threonine kinase important in vascular smooth muscle relaxation and platelet aggregation inhibition.
It regulates cardiovascular and neuronal functions, smooth muscle tone, and cell growth.
Highly expressed in smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala.
Isoforms Iα and Iβ share identical cGMP-binding and catalytic domains but differ in leucine/isoleucine zipper and autoinhibitory sequences, resulting in distinct dimerization substrates and kinase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.