Thermo Fisher Scientific Talizumab Chimeric Recombinant Human Monoclonal Antibody
Talizumab 키메라 재조합 인간 단일클론 항체로 IgE를 표적으로 하며 알레르기 반응 연구에 사용됩니다. CHO 세포 발현, Protein A 정제, 액상 형태로 제공되며, 보존제 무첨가 상태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA542310
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Talizumab Chimeric Recombinant Human Monoclonal Antibody
Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Human / IgG4, kappa / IgG4, lambda |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | IgE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.18 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911452 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Talizumab is a biosimilar that targets IgE.
IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with four Ig-like constant domains and two light chains.
IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, and anaphylactic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils, promoting allergic manifestations.
IgE is also functionally important for immunity against parasites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.