Thermo Fisher Scientific TET3 Polyclonal Antibody
TET3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 사용 가능. 인간, 생쥐, 랫트 반응성. 합성 펩타이드 항원을 이용해 제작되었으며, 액상 형태로 1 mg/mL 농도. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TET3 (Accession O43151), corresponding to amino acid residues S799–C849 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900660 |
Product Specific Information
This antibody detects endogenous levels of total TET3.
Target Information
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and is suggested to play a role in epigenetic reprogramming of zygotic paternal DNA following fertilization, as well as in somatic cell nuclear reprogramming during animal cloning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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