Thermo Fisher Scientific Complement C4 Polyclonal Antibody
Thermo Fisher Scientific의 Complement C4 Polyclonal Antibody는 인간 C4 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며, 고순도의 Protein A 정제 항체로 안정적인 신호를 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human C4 protein, Asn975–Arg1336 (Accession #P0C0L4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093674 |
Target Information
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor that is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen–antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have one, two, or three copies of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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