Thermo Fisher Scientific RNF41 Monoclonal Antibody (4C2)
RNF41 단백질을 인식하는 Mouse IgM 단클론 항체로 Western blot 및 ELISA에 적합. 휴먼 및 랫트 반응성. 비결합형 액상 형태이며 -20°C에서 보관. 단백질 분해 관련 유비퀴틴화 경로 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C2 |
| Immunogen | RNF41 (NP_005776, 218–317 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ISTPDAVLQA VIKRSLVESG CPASIVNELI ENAHERSWPQ GLATLETRQM NRRYYENYVA KRIPGKQAVV VMACENQHMG DDMVQEPGLV MIFAHGVEEI
Target Information
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and consists of a conserved cysteine-rich domain capable of binding two zinc atoms. Proteins containing this domain are typically involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein with one RING-type zinc finger and one SIAH-type zinc finger. It is expressed in testis, ovary, and prostate, and functions as an E3 ubiquitin-protein ligase. Nrdp1 interacts with ErbB-3 and UBPY, targeting them for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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