Thermo Fisher Scientific NSG1 Polyclonal Antibody
NSG1 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체로, 인간·생쥐·랫드에 반응합니다. Western blot, ICC/IF, IHC(PFA) 등 다양한 응용에 적합하며, 고순도 액상 형태로 제공됩니다. 신경세포 성숙 관련 연구용으로 사용됩니다.
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Thermo Fisher Scientific NSG1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1–5 µg/mL | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence EKGTKQPLLEDGFD-C from N-terminus of Nsg1 (aa 10–23) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554545 |
Product Specific Information
- Predicted to react with human and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
NEEP21 (neuron-enriched endosomal 21kDa protein), also known as NSG1, is a single-pass type II membrane protein of the NSG family.
It is highly expressed during neuronal maturation and downregulated in adult tissues.
NEEP21 localizes to Rab4-positive early endosomes in neurons and is essential for receptor sorting and recycling.
It interacts with GRIP1 and GluR-2, mediating GluR-2 surface expression. Disruption of this interaction causes GluR-2 accumulation in early endosomes and alters synaptic current properties.
NEEP21 also forms complexes with Syntaxin 13 and participates in recycling of transferrin receptors (TFRs) and neurotensin receptor 2 (NTR2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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