ELK Biotechnology ABHD7 rabbit pAb
ABHD7 rabbit pAb은 인간 및 마우스에서 반응하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 합성 펩타이드(AA 101–150)를 면역원으로 사용하였으며, 42kD 밴드를 검출합니다. α/β hydrolase 슈퍼패밀리 단백질 연구에 활용됩니다.
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제품명
ABHD7 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EPHX4; ABHD7; EPHXRP; Epoxide hydrolase 4; Abhydrolase domain-containing protein 7; Epoxide hydrolase-related protein |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ABHD7 (AA range: 101–150) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 253152 |
| Human Swiss-Prot No | Q8IUS5 |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Species Reactivity | Human; Mouse |
Background
The α/β hydrolase superfamily comprises diverse members involved in important biochemical processes and various diseases. Despite unrelated sequences and substrate diversity, they share a canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad (histidine, acid, nucleophile).
Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
The Ab hydrolase domain containing (ABHD) gene subfamily includes 15 mostly uncharacterized members, most of which utilize a serine nucleophile forming the G-X-S-X-G nucleophile elbow.
ABHD7 is a 362 amino acid single-pass type II membrane protein belonging to the AB hydrolase superfamily and the Epoxide hydrolase family.
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