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ELK Biotechnology Separase (phospho Ser801) rabbit pAb
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인산화된 Ser801 부위를 인식하는 Separase 특이적 rabbit polyclonal 항체로, WB, IHC, IF, ELISA에 사용 가능. 세포 내 분리효소 연구에 적합하며, 고농도(1 mg/ml)로 -20°C에서 1년 보관 가능.
- 카탈로그번호
- ES1518-xxxxx (2개 옵션)
- 판매단위
- pk
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카탈로그 번호 · 상품 설명출고판매가담기
ELK Biotechnology ES1518-100UL Separase (phospho Ser801) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1518-50UL Separase (phospho Ser801) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Separase (phospho Ser801) rabbit pAb
Separase (phospho Ser801) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Separase (phospho Ser801) rabbit pAb |
| Alternative Names | ESPL1; ESP1; KIAA0165; Separin; Caspase-like protein ESPL1; Extra spindle poles-like 1 protein; Separase |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SEPARASE around the phosphorylation site of Ser801. AA range: 767-816 |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 230 kD |
| Gene ID (Human) | 9700 |
| Human Swiss-Prot No. | Q14674 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Mouse |
Background
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in two steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]). [Supplied by OMIM, Nov 2010]
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