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ELK Biotechnology PFK-2 car (phospho Ser483) rabbit pAb
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ELK Biotechnology PFK-2 car (phospho Ser483) rabbit pAb

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PFK-2 car (phospho Ser483) rabbit polyclonal antibody로, 인산화된 Ser483 부위의 PFKFB2 단백질을 검출합니다. WB, IHC, IF, ELISA에 사용 가능하며, 사람·생쥐·쥐 시료에 반응합니다. 고순도 IgG, 1 mg/ml 농도로 제공됩니다.

판매단위
pk
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ELK Biotechnology ES1490-100UL PFK-2 car (phospho Ser483) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1490-50UL PFK-2 car (phospho Ser483) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology PFK-2 car (phospho Ser483) rabbit pAb

PFK-2 car (phospho Ser483) Rabbit pAb

제품 정보

항목 내용
Product name PFK-2 car (phospho Ser483) rabbit pAb
Alternative Names PFKFB2; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500–1/2000
Immunohistochemistry: 1/100–1/300
ELISA: 1/40000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human PFKFB2 around the phosphorylation site of Ser483 (AA range: 451–500)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 58 kD
Gene ID (Human) 5208
Human Swiss-Prot No. O60825
Cellular Localization Cytosol
Species Reactivity Human; Mouse; Rat

Background

The protein encoded by this gene participates in both the synthesis and degradation of fructose-2,6-bisphosphate, a key regulatory molecule controlling glycolysis in eukaryotic cells. It possesses dual enzymatic activities:

  • 6-phosphofructo-2-kinase activity, catalyzing the synthesis of fructose-2,6-bisphosphate
  • Fructose-2,6-bisphosphatase activity, catalyzing its degradation

This enzyme regulates fructose-2,6-bisphosphate levels in the heart, while related enzymes control levels in the liver and muscle. It functions as a homodimer, and two transcript variants encoding different isoforms have been identified (RefSeq, Jul 2008).

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