Thermo Fisher Scientific FHL2 Polyclonal Antibody
FHL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC(P), ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제 및 안정적 PBS/glycerol 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FHL2 (Accession Q14192), corresponding to amino acid residues D205–S255 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899868 |
Product Specific Information
Antibody detects endogenous levels of total FHL2.
Target Information
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged zinc finger domains, each binding a zinc atom via four conserved cysteines.
The FHL2 protein is involved in extracellular membrane assembly and is down-regulated during the transformation of normal myoblasts to rhabdomyosarcoma cells. It may act as a link between presenilin-2 and intracellular signaling pathways. Multiple alternatively spliced variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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