Thermo Fisher Scientific CD6 Monoclonal Antibody (01)
Rat CD6 단백질을 인식하는 Mouse IgG2a 단클론 항체. Flow Cytometry에 적합하며 비결합형 액상 형태로 제공. Protein A로 정제되어 높은 순도 보장. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:25–1:100
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 01 |
| Immunogen | Recombinant Rat CD6 / Cluster of Differentiation 6 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866667 |
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL).
CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6–ALCAM mediated cell adhesion is also important for T cell proliferation.
CD6 may exert some of its functions via association with CD5, probably by fine-tuning CD5 signaling.
Ligation of CD6 has an antiapoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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