Thermo Fisher Scientific SMAD6 Polyclonal Antibody
SMAD6 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 최적화됨. 인간에 반응하며 마우스에도 예측 반응. Protein A 및 항원 친화 크로마토그래피로 정제됨. PBS 완충액(0.09% sodium azide) 내 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 358–386 amino acids from the central region of human SMAD6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542763 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
SMAD6 (mothers against decapentaplegic homolog 6) acts as an antagonist of signaling by TGF-beta type 1 receptor superfamily members. It selectively inhibits BMP (bone morphogenetic protein) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is classified as an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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