Thermo Fisher Scientific GRAMD2 Polyclonal Antibody
Human GRAMD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 시약으로, 액상 형태이며 0.5 mg/mL 농도. ER-플라즈마막 접촉 부위 연구 및 칼슘 항상성 관련 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human GRAMD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688746 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% | Dog: 100% | Guinea Pig: 100% | Horse: 93% | Human: 100% | Mouse: 93% | Rabbit: 86% | Rat: 93%
Target Information
Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis.
Acts as a constitutive tether that co-localizes with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner.
Pre-marks a subset of phosphatidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store-operated calcium entry pathway (SOCE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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