Thermo Fisher Scientific FAT4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human FAT4 protein. Validated for Western blot and immunoprecipitation. Unconjugated, liquid form, 1 mg/mL concentration. Suitable for research use with predicted mouse reactivity.
- 카탈로그번호
- A305883Ax (2개 옵션)
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 8–15 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 4931 and 4981 of human Protocadherin Fat 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Predicted reactivity by homology: Mouse.
Target Information
FAT1, FAT2, FAT3, and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergoes proteolytic cleavage by Furin and secretase to release the intracellular domain (ICD). It directly interacts with MPDZ/MUPP1 to recruit membrane-associated guanylate kinase MPP5/PALS1. FAT4 plays a role in maintaining PCP and inhibiting cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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