Thermo Fisher Scientific H3R17me2s Polyclonal Antibody
H3R17me2s 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응. Western blot, ICC/IF, ELISA에 적합. 합성 디메틸화 펩타이드 면역원 사용. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic symmetric dimethylated peptide around R17 of human histone H3 (NP_0035201) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806337 |
Product Specific Information
- Positive Samples: HeLa, H3 protein
- Cellular Location: Chromosome, Nucleus
- Immunogen Sequence: APRKQ
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. It, along with four core histone proteins, binds to DNA forming the nucleosome structure. Histones are crucial for transcription regulation, DNA repair, replication, and chromosomal stability.
The N-terminal tail of histone H3 can undergo post-translational modifications such as methylation, acetylation, and phosphorylation, influencing chromatin structure and transcription factor binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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