Thermo Fisher Scientific prgI Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Salmonella typhimurium Protein prgI (prgI) (1-80AA)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.95 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% Proclin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_3091640

Target Information

Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:16501225, PubMed:12754250, PubMed:30242280, PubMed:33750771). PrgI/SctF1 forms the external needle filament that protrudes from the bacterial surface (PubMed:16501225, PubMed:12754250, PubMed:22699623, PubMed:30242280, PubMed:31260457, PubMed:33750771). Is probably involved in the transduction of an activating signal, thought to be mediated by the distal tip of the needle filament, to the secretion machine (PubMed:31260457). Required for invasion of epithelial cells (PubMed:17617421). Required for the secretion of the effector protein SptP (PubMed:31260457, PubMed:33750771).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.