Thermo Fisher Scientific DHCR24 Polyclonal Antibody
DHCR24 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 1 mg/mL 농도이며, 장기 보관 시 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human DHCR24 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719913 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase that catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence directing it to the endoplasmic reticulum membrane. Missense mutations in this gene are associated with desmosterolosis. Reduced expression of DHCR24 has been observed in the temporal cortex of Alzheimer’s disease patients, while overexpression has been reported in adrenal gland cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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