Thermo Fisher Scientific OTC Monoclonal Antibody (OTI1C4), TrueMAB
OTC 단백질을 표적으로 하는 마우스 모노클로날 항체로, Western blot 및 면역조직화학(파라핀 절편)에서 검증됨. 무보존제, 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 인간 단백질 반응성, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–354 of human OTC produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7 K MWCO, 0.5 mL, Product #89882).
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Mutations (missense, nonsense, frameshift) in this enzyme cause ornithine transcarbamylase deficiency, leading to hyperammonemia.
The gene is located near the Duchenne muscular dystrophy gene and may be implicated in that disease as well.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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