Thermo Fisher Scientific SLC16A3 Polyclonal Antibody
SLC16A3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer 보존. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publication |
| ELISA | 1 µg/mL | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing sequence corresponding to amino acids 410–465 of human MCT4/SLC16A3 (NP_0041981) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804558 |
Product Specific Information
- Positive Samples: HT-1080, SW620, MCF7, Rat skeletal muscle
- Cellular Location: Cell membrane, Multi-pass membrane protein
- Immunogen Sequence:
IRKKPKEPQP EVAAAEEEKL HKPPADSGVD LREVEHFLKA EPEKNGEVVH TPETSV
Target Information
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, designated solute carrier family-16. Each MCT shows distinct substrate and inhibitor specificities and transport kinetics, reflecting the metabolic requirements of its tissue localization. MCTs, including MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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