Thermo Fisher Scientific hnRNP A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting hnRNP A1 for WB and ICC/IF applications. Recognizes amino acids 1–140 of human hnRNP A1. Suitable for detecting cytoplasmic and nuclear localization in various cell types. Supplied as liquid, 0.7 mg/mL, stored at -2...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–140 of human hnRNP A1 (NP_002127.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804990 |
Product Specific Information
Immunogen sequence:
MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN TKRSRGFGFV TYATVEEVDA AMNARPHKVD GRVVEPKRAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH LRDYFEQYGK IEVIEIMTDRPositive Samples:
HeLa, 293T, HepG2, MCF-7, SW620, Mouse brain, Mouse spinal cord, Rat brain, Rat spinal cordCellular Location:
Cytoplasm, Nucleus
Target Information
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These RNA-binding proteins complex with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport. hnRNP A1 contains two quasi RRM domains that bind RNAs and is localized to the nucleoplasm. It is one of the most abundant core proteins of hnRNP complexes and shuttles between the nucleus and cytoplasm, likely bound to mRNA.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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