Thermo Fisher Scientific PDE3B Polyclonal Antibody
Human PDE3B 인식 polyclonal antibody로 Western blot에 적합. Rabbit IgG로 제작되었으며 Affinity Chromatography로 정제됨. PBS + sucrose buffer에 보관하며 -20°C에서 안정적. cAMP/cGMP 신호 조절 연구에 활용 가능.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PDE3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607940 |
Product Specific Information
- Peptide sequence: SRPEYNFLLH LDHVEFKRFR FLVIEAILAT DLKKHFDFLA EFNAKANDVN
- Sequence homology:
Cow: 86%
Dog: 93%
Guinea Pig: 86%
Horse: 93%
Human: 100%
Mouse: 86%
Pig: 93%
Rabbit: 93%
Rat: 93%
Zebrafish: 79%
Target Information
Cyclic nucleotide phosphodiesterase with dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many physiological processes.
May play a role in fat metabolism and regulates cAMP binding of RAPGEF3.
Through simultaneous binding to RAPGEF3 and PIK3R6, assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and is involved in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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