Thermo Fisher Scientific SERPINA3 Monoclonal Antibody (1E6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1E6

Immunogen

SERPINA3 (AAH03559, 25 a.a. approximately 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SERPINA3,uniProtId:P01011-1,ncbiNodeId:9606,antigenRange:25-423,antigenLength:423,antigenImageFileName:H00000012-M01A_SERPINA3_P01011-1_House_mouse.svg,antigenImageFileNamePDP:H00000012-M01A_SERPINA3_P01011-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PNSPLDEENL TQENQDRGTH VDLGLASANV DFAFSLYKQL VLKAPDKNVI FSPLSISTAL AFLSLGAHNT TLTEILKGLK FNLTETSEAE IHQSFQHLLR TLNQSSDELQ LSMGNAMFVK EQLSLLDRFT EDAKRLYGSE AFATDFQDSA AAKKLINDYV KNGTRGKITD LIKDLDSQTM MVLVNYIFFK AKWEMPFDPQ DTHQSRFYLS KKKWVMVPMM SLHHLTIPYF RDEELSCTVV ELKYTGNASA LFILPDQDKM EEVEAMLLPE TLKRWRDSLE FREIGELYLP KFSISRDYNL NDILLQLGIE EAFTSKADLS GITGARNLAV SQVVHKAVLD VFEEGTEASA ATAVKITLLS ALVETRTIVR FNRPFLMIIV PTDTQNIFFM SKVTNPKQA

Target Information

SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer`s disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.