Thermo Fisher Scientific ELL Monoclonal Antibody (OTI3E9), TrueMAB
ELL 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 안정적인 PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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- TA810825
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 302–621 of human ELL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
Also a component of the little elongation complex (LEC), which regulates small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
ELL plays an early role before its assembly into the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site.
Required to stabilize the pre-initiation complex and early elongation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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