Thermo Fisher Scientific CDH4 Polyclonal Antibody
CDH4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow Cytometry에 사용 가능. 인간 시료에 반응하며, 마우스 및 랫과의 교차 반응 예측. Protein A 및 항원 친화 크로마토그래피로 정제된 액상 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 175–203 of the N-terminal region of human CDH4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2077779 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
CDH4 (Cadherin-4) is a classical cadherin belonging to the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. Studies suggest roles in brain segmentation, neuronal outgrowth, kidney, and muscle development. CDH4 can form stable cis-heterodimers with cadherin-2 (CDH2), providing evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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