Thermo Fisher Scientific CHD9 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500

Product Specifications

Product Specific Information

Immunogen sequence:
HQVESQTEPF TGLDPEDLLQ EGLLPHFDES TFGQDNSSHI LDHDLDRQFT SHLVTRPSDM AQTQLQSQAR SWHSSFSNHQ HLHDRNHLCL QRQPPSSKKS DGSGTYTKLQ NTQV

Highest antigen sequence identity to the following orthologs:

• Mouse: 85%
• Rat: 81%

Target Information

CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2, or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family.
The CHD family of proteins are ATP-dependent chromatin remodeling enzymes combining chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability.
Localized to the cytoplasm and nucleus, CHD9 contains two chromodomains, one ATP-binding helicase domain, and one C-terminal helicase domain. Chromodomains (40–50 amino acids) are conserved across plants and animals and are found in many chromatin-associated proteins.
CHD9 acts as a transcriptional coactivator for PPARα and may function as an ATP-dependent chromatin remodeling protein.
CHD9 is widely expressed at low levels and exists as three isoforms produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.