
Thermo Fisher Scientific CHD9 Polyclonal Antibody
CHD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P) 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로, 장기 보관 시 -20°C에서 안정적. 연구용 전용 제품.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHD9. Recombinant protein control fragment (Product #RP-98770). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639760 |
Product Specific Information
Immunogen sequence:
HQVESQTEPF TGLDPEDLLQ EGLLPHFDES TFGQDNSSHI LDHDLDRQFT SHLVTRPSDM AQTQLQSQAR SWHSSFSNHQ HLHDRNHLCL QRQPPSSKKS DGSGTYTKLQ NTQV
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 81%
Target Information
CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2, or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family.
The CHD family of proteins are ATP-dependent chromatin remodeling enzymes combining chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability.
Localized to the cytoplasm and nucleus, CHD9 contains two chromodomains, one ATP-binding helicase domain, and one C-terminal helicase domain. Chromodomains (40–50 amino acids) are conserved across plants and animals and are found in many chromatin-associated proteins.
CHD9 acts as a transcriptional coactivator for PPARα and may function as an ATP-dependent chromatin remodeling protein.
CHD9 is widely expressed at low levels and exists as three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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