Thermo Fisher Scientific AGK Polyclonal Antibody
Rabbit polyclonal antibody against human AGK. Validated for IHC (paraffin) with 1:200–1:500 dilution. Recognizes AGK recombinant protein. Suitable for research on lipid kinase signaling and EGFR/MAPK pathways. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AGK. Recombinant protein control fragment (Product # RP-92596) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637759 |
Product Specific Information
Immunogen sequence:
LHLSGMDVTI VKTDYEGQAK KLLELMENTD VIIVAGGDGT LQEVVTGVLR RTDEATFSKI PIGFIPLGET SSLSHTLFAE SGNKV
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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