
Thermo Fisher Scientific CDH4 Monoclonal Antibody (OTI4D9), TrueMAB
인간 CDH4 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot에 최적화됨. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 세포-세포 접착 연구 및 신경 발달 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 170–428 of human CDH4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CDH4 is a classical cadherin from the cadherin superfamily. It encodes a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. Studies in chicken and mouse indicate roles in brain segmentation, neuronal outgrowth, kidney, and muscle development. CDH4 can form stable cis-heterodimers with cadherin 2, providing evidence of heterodimerization among cadherins. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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