Thermo Fisher Scientific CPSF4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CPSF4 protein. Validated for Western blot and ELISA applications. Supplied as a liquid, affinity-purified, unconjugated antibody in PBS with glycerol. Recommended storage at -20°C. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–244 of human CPSF4 (NP_001075028.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.14 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804400 |
Product Specific Information
Immunogen sequence:
MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHI SGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESK IKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPP LPQQTQPPAK QRTPQVIGVM QSQNSSAGNR GPRPLEQVTC YKCGEKGHYA NRCTKGHLAF LSGQ
Positive Samples: HeLa, Jurkat, 22Rv1
Cellular Location: Nucleus
Target Information
CPSF4 (Cleavage and Polyadenylation Specific Factor 4) is an essential component of the 3′ end processing machinery of cellular pre-mRNAs. The influenza A virus NS1 protein interacts with CPSF4, inhibiting the nuclear export of poly(A)-containing mRNAs in infected cells. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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