Thermo Fisher Scientific MIF (Macrophage Migration Inhibitory Factor) Monoclonal Antibody (MIF/6283)
인간 MIF 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC 등 다양한 응용에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관합니다. 면역 및 염증 연구용으로 사용됩니다.
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Thermo Fisher Scientific MIF (Macrophage Migration Inhibitory Factor) Monoclonal Antibody (MIF/6283)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MIF/6283 |
| Immunogen | Recombinant fragment of human MIF protein (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MIF (macrophage migration inhibitory factor) was one of the first cytokine activities discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989).
Recently, MIF was rediscovered as a pituitary hormone acting as a counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995).
MIF is released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998).
MIF plays a critical role in host control of inflammation and immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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