
Thermo Fisher Scientific GREM1 Polyclonal Antibody
Thermo Fisher Scientific의 GREM1 Polyclonal Antibody는 Mouse 및 Rat에 반응하며 Western Blot에 적합합니다. Rabbit IgG 폴리클로날 항체로, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태, 0.5 mg/mL 농도이며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of rat GREM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691293 |
Product Specific Information
This target displays homology in the following species:
Cow: 92%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 93%
Target Information
In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine, and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, supporting the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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