Thermo Fisher Scientific GPR110 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GPR110 for IHC(P) applications. Recognizes N-terminal extracellular domain. High purity via antigen affinity chromatography. Supplied as liquid (1 mg/mL) in PBS with 0.1% sodium azide. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPR110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550987 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon: 100%
- Marmoset: 88%
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, are a superfamily of proteins that mediate various stimulus-response pathways. They translate extracellular signals into intracellular responses via G protein activation and respond to signaling molecules such as hormones and neurotransmitters.
GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911-amino-acid protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. It is characterized as an adhesion GPCR, a multipass membrane-bound protein with a long amino-terminus containing multiple domains, including a GPCR proteolytic site (GPS) essential for proteolytic cleavage and cell surface expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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