
Thermo Fisher Scientific SRC Family Negative Regulatory (pY) Site Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
View 2 publications 2 publications
Product Specifications
Published species
Mouse
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthesized phosphopeptide derived from the region of human Hck that contains tyrosine 522. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
SRC Family Negative Regulatory (pY) Site,
uniProtId:
P12931-1,
ncbiNodeId:
9606,
antigenRange:
522,
antigenLength:
536,
antigenImageFileName:
44-912_SRC_Family_Negative_Regulatory_pY_Site_P12931-1_Rabbit.svg,
antigenImageFileNamePDP:
44-912_SRC_Family_Negative_Regulatory_pY_Site_P12931-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533793
Target Information
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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