Thermo Fisher Scientific SRC Family Negative Regulatory (pY) Site Polyclonal Antibody
SRC 패밀리 음성 조절 인산화 부위(pY) 인식 폴리클로날 항체로, Western blot에 최적화됨. Rabbit IgG 호스트에서 유래했으며, 비결합형 액상 형태로 제공. 인간 Hck의 Tyr522 인산화 펩타이드 면역원 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized phosphopeptide derived from the region of human Hck that contains tyrosine 522 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533793 |
Target Information
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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