Thermo Fisher Scientific DDX3 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. DDX3 단백질 연구용으로 RNA 헬리케이스 관련 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human DDX3 aa 220–420 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2932537 |
Target Information
The protein encoded by this gene is a member of the large DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif, and exhibits ATP-dependent RNA helicase activity. It displays high RNA-independent ATPase activity, stimulated by both RNA and DNA. This protein functions in both the nucleus and cytoplasm, participating in transcriptional regulation, mRNP assembly, pre-mRNA splicing, mRNA export, translation, cellular signaling, and viral replication. Misregulation of this gene has been linked to tumorigenesis. It has a paralog on the Y chromosome, and pseudogenes are found on chromosome 4 and the X chromosome. Multiple transcript variants arise from alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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