Thermo Fisher Scientific Cripto Polyclonal Antibody, Biotin
Cripto 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal 항체. Western blot, ICC/IF, Flow cytometry에 적합. Human 및 Mouse 시료 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
- 카탈로그번호
- PA522698
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cripto Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | |
| Immunocytochemistry (ICC/IF) | 1:1,000 | |
| Flow Cytometry (Flow) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an N-terminal portion of the murine Cripto protein sequence (between residues 1–50). |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151971 |
Product Specific Information
In Western blot, a band is seen at approximately 18 kDa representing the core form of Cripto1, and at approximately 36 kDa representing the glycosylated or post-translationally modified form.
Suggested positive control: MDA-MB231 (human breast cancer) lysates.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in embryonic stem cells and during early embryo development, and is reactivated in a wide range of epithelial cancers in adults.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.