Thermo Fisher Scientific EPO Monoclonal Antibody (OTI5D8), TrueMAB
인간 EPO 단백질을 인식하는 마우스 단클론 항체로 Western Blot에 적합. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 버퍼에 보존. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 28–193 of human EPO produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Erythropoietin (EPO) is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. It induces final maturation of partially differentiated erythroid cells and stimulates production of red cell-specific proteins such as hemoglobin. The EPO receptor (EPOR) is highly expressed on precursor cells and decreases with maturation. During fetal development, hepatocytes are the main source of EPO, while in adults it is produced primarily by kidney interstitial cells. EPO expression increases under hypoxic conditions and is also detected in lung and brain tissue. Recent studies suggest EPO may protect neuronal tissue and aid in repair processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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