Thermo Fisher Scientific Phospho-PDE4A (Thr34) Polyclonal Antibody, Biotin
PKA 인산화 부위에 특이적인 Phospho-PDE4A (Thr34) 항체. Western blot, ELISA, IP에 적합. Human, Mouse, Rat 반응성. Biotin 결합된 Rabbit Polyclonal 형태로, 신호전달 연구에 유용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to PKA phosphorylation site on PDE4A long form enzymes. The peptide was synthesized with phosphorylated serine residue. |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals such as hormones, light, and neurotransmitters.
Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction.
PDE4A is a class IV cAMP-specific phosphodiesterase.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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