Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI3C12), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The DOK7 protein is essential for neuromuscular synaptogenesis. It mediates aneural activation of muscle-specific receptor kinase, required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes.
Mutations in DOK7 are associated with familial limb-girdle myasthenia (congenital myasthenic syndrome type 1B).
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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