Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI3C12), TrueMAB
인간 DOK7 단백질을 인식하는 단클론 항체로, Western blot 및 유세포 분석에 최적화됨. 마우스 IgG2b 아이소타입, 비결합형 상태로 제공. 고순도 친화 크로마토그래피 정제, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C12 |
| Immunogen | Full length human recombinant protein of human DOK7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DOK7 protein is essential for neuromuscular synaptogenesis. It mediates aneural activation of muscle-specific receptor kinase, required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes.
Mutations in DOK7 are associated with familial limb-girdle myasthenia (congenital myasthenic syndrome type 1B).
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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