Thermo Fisher Scientific RAB3GAP1 Polyclonal Antibody
RAB3GAP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 IHC, ICC, ELISA 등에 사용 가능. KLH 결합 합성 펩타이드(aa 501-600)로부터 유래. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RAB3GAP1, amino acids 501–600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RAB3GAP1 is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP and is required for normal eye and brain development.
Defects in Rab3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia.
The Rab3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration, and differentiation before synapse formation, as well as in non-synaptic vesicular release of neurotransmitters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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