Thermo Fisher Scientific ZNF265 Monoclonal Antibody (2A11)
ZNF265 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(2A11). Western blot 및 ELISA에 사용 가능하며, 인간, 마우스, 랫트 반응성. PBS 용액 형태, 보존제 없음, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A11 |
| Immunogen | ZNF265 (NP_005446, 1–106 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MSTKNFRVSD GDWICPDKKC GNVNFARRTS CNRCGREKTT EAKMMKAGGT EIGKTLAEKS RGLFSANDWQ CKTCSNVNWA RRSECNMCNT PKYAKLEERT GYGGGF
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, including transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2, ZIS, ZIS1, or ZIS2, is a 330 amino acid protein of the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5′-splice selection.
It contains two RanBP2-type zinc fingers enabling RNA-binding activity.
Two isoforms (ZIS-1 and ZIS-2) arise from alternative splicing. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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