Thermo Fisher Scientific ZMIZ2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZMIZ2. Recombinant protein control fragment (Product #RP-89718). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZMIZ2,uniProtId:Q8NF64-1,ncbiNodeId:9606,antigenRange:712-827,antigenLength:920,antigenImageFileName:PA5-59263_ZMIZ2_Q8NF64-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59263_ZMIZ2_Q8NF64-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649937

Product Specific Information

Immunogen sequence: LMPSVMEMIA ALGPGAAPFA PLQPPSVPAP SDYPGQGSSF LGPGTFPESF PPTTPSTPTL AEFTPGPPPI SYQSDIPSSL LTSEKSTACL PSQMAPAGHL DPTHNPGTPG LHTSNL

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

Target Information

ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.