Thermo Fisher Scientific FBLIM1 Monoclonal Antibody (OTI3F8), TrueMAB

Applications

• Western Blot (WB)
  • Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The FBLIM1 gene encodes a protein containing:

• N-terminal filamin-binding domain
• Central proline-rich domain
• Multiple C-terminal LIM domains

This protein localizes at cell junctions and links cell adhesion structures to the actin cytoskeleton.
It plays roles in:

• Assembly and stabilization of actin filaments
• Modulation of cell adhesion, morphology, and motility

Additionally, FBLIM1 localizes to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor.
Alternative splicing produces multiple isoforms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.