Thermo Fisher Scientific FBLIM1 Monoclonal Antibody (OTI3F8), TrueMAB
인간 FBLIM1 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화되어 있습니다. Carrier-free 형태로 제공되어 직접적인 결합 실험에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 세포 접착 및 형태 연구에 활용 가능합니다.
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- CF807272
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- pk
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Applications
- Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–242 of FBLIM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The FBLIM1 gene encodes a protein containing:
- N-terminal filamin-binding domain
- Central proline-rich domain
- Multiple C-terminal LIM domains
This protein localizes at cell junctions and links cell adhesion structures to the actin cytoskeleton.
It plays roles in:
- Assembly and stabilization of actin filaments
- Modulation of cell adhesion, morphology, and motility
Additionally, FBLIM1 localizes to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor.
Alternative splicing produces multiple isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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