Thermo Fisher Scientific alpha Tubulin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100

-

Immunocytochemistry (ICC/IF)

2 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide derived from aa 426-450 of human tubulin alpha if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha Tubulin,uniProtId:P68363-1,ncbiNodeId:9606,antigenRange:426-450,antigenLength:451,antigenImageFileName:PA5-16891_alpha_Tubulin_P68363-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16891_alpha_Tubulin_P68363-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:alpha Tubulin,uniProtId:Q71U36-1,ncbiNodeId:9606,antigenRange:426-450,antigenLength:451,antigenImageFileName:PA5-16891_alpha_Tubulin_Q71U36-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16891_alpha_Tubulin_Q71U36-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:alpha Tubulin,uniProtId:P0DPH7-1,ncbiNodeId:9606,antigenRange:426-450,antigenLength:450,antigenImageFileName:PA5-16891_alpha_Tubulin_P0DPH7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16891_alpha_Tubulin_P0DPH7-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:alpha Tubulin,uniProtId:Q6PEY2-1,ncbiNodeId:9606,antigenRange:426-450,antigenLength:450,antigenImageFileName:PA5-16891_alpha_Tubulin_Q6PEY2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16891_alpha_Tubulin_Q6PEY2-1_Rabbit_PDP.jpeg,sortOrder:6}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.6, with 1% BSA

Contains

0.1% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984790

Product Specific Information

PA5-16891 targets Tubulin alpha in immunohistochemistry (paraffin) and Western blot applications and shows reactivity with Bovine, Chicken, amphibian, Gerbil, Guinea Pig, Human, mouse, Porcine, and Rat samples.

The PA5-16891 immunogen is a synthetic peptide derived from aa 426-450 of human tubulin alpha.

Target Information

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.