Thermo Fisher Scientific GPR17 Polyclonal Antibody
Thermo Fisher Scientific의 GPR17 Polyclonal Antibody는 인간 GPR17 단백질을 인식하는 토끼 유래 IgG 항체입니다. IHC 및 ICC/IF 실험에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA533658
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 3–16 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPR17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551036 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%).
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members and represents the largest known class of molecular targets with therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in the orchestration of oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) inhibition of adenylyl cyclase.
It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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