Thermo Fisher Scientific CCDC67 Polyclonal Antibody
인간 CCDC67 단백질에 특이적인 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보존. 단백질 상호작용 및 중심체 생합성 연구에 적합.
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- PA552768
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CCDC67. Recombinant protein control fragment (Product # RP-90402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639478 |
Product Specific Information
Immunogen sequence:
MKQNKVPRKE LPHLKEEIPF ELSNLNQKLE EFRAKSREWD KQEILYQTHL ISLDAQQKLL SEKCNQFQKQ AQSYQTQLNG KKQCLEDSSS EIPRLICDPD PNCEINERDE FIIEKLKSAV NEIALSRNKL QD
Antigen sequence identity:
- Mouse: 83%
- Rat: 80%
Target Information
Gene/Protein: CCDC67 (Deuterosome Assembly Protein 1)
CCDC67 is a key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. It likely contributes to the specification and formation of the deuterosome inner core. The protein interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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