Thermo Fisher Scientific CCDC67 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CCDC67. Recombinant protein control fragment (Product #RP-90402). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC67,uniProtId:Q05D60-1,ncbiNodeId:9606,antigenRange:115-246,antigenLength:604,antigenImageFileName:PA5-52768_CCDC67_Q05D60-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52768_CCDC67_Q05D60-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639478

Product Specific Information

Immunogen sequence: MKQNKVPRKE LPHLKEEIPF ELSNLNQKLE EFRAKSREWD KQEILYQTHL ISLDAQQKLL SEKCNQFQKQ AQSYQTQLNG KKQCLEDSSS EIPRLICDPD PNCEINERDE FIIEKLKSAV NEIALSRNKL QD

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

Target Information

CCDC67 (deuterosome assembly protein 1) is a key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. The protein interacts with CEP152 and recruits PLK4 to activate centriole biogenesis

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.