Thermo Fisher Scientific RBFOX3 Monoclonal Antibody (OTI2E5), TrueMAB
RBFOX3(NeuN) 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 적합하며, 인간 시료에 반응. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–97 of human RBFOX3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Fox-3, also known as NEUN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein that contains one RRM (RNA recognition motif) domain. Localized to both the nucleus and cytoplasm, Fox-3 is suggested to regulate alternative splicing events.
Fox-3 is encoded by a gene located on human chromosome 17, which encodes over 1,200 genes and includes key tumor suppressors such as p53 and BRCA1.
- p53: Maintains genetic integrity by balancing DNA repair and apoptosis.
- BRCA1: Involved in DNA repair, associated with early-onset breast and ovarian cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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